Phenotypes associated with this allele

• Allele Symbol: Dsg2^{tm1b(EUCOMM)Wtsi}
• Allele Name: targeted mutation 1b, Wellcome Trust Sanger Institute
• Allele ID: MGI:5792555
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Dsg2^tm1b(EUCOMM)Wtsi/Dsg2^tm1b(EUCOMM)Wtsi	C57BL/6N-Dsg2^tm1b(EUCOMM)Wtsi/Bay	MGI:6288430

Genotype
MGI:6288430

hm1

• Allelic Composition: Dsg2^{tm1b(EUCOMM)Wtsi}/Dsg2^{tm1b(EUCOMM)Wtsi}
• Genetic Background: C57BL/6N-Dsg2^{tm1b(EUCOMM)Wtsi}/Bay
• Cell Lines: EPD0156_5_D01

Data Sources

IMPC Data for Dsg2

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

increased heart weight ( J:211773 )

♀

IMPC - BCM

dilated heart left ventricle ( J:211773 )

IMPC - BCM

decreased cardiac muscle contractility ( J:211773 )

IMPC - BCM

growth/size/body

increased heart weight ( J:211773 )

♀

IMPC - BCM

homeostasis/metabolism

decreased circulating glucose level ( J:211773 )

♀

IMPC - BCM

decreased circulating alkaline phosphatase level ( J:211773 )

♀

IMPC - BCM

decreased circulating serum albumin level ( J:211773 )

♀

IMPC - BCM

decreased circulating total protein level ( J:211773 )

♀

IMPC - BCM

integument

abnormal coat appearance ( J:211773 )

♂

IMPC - BCM

mortality/aging

preweaning lethality, incomplete penetrance ( J:211773 )

♂

IMPC - BCM

muscle

decreased cardiac muscle contractility ( J:211773 )

IMPC - BCM