Phenotypes associated with this allele

• Allele Symbol: Snapc2^em1(IMPC)J
• Allele Name: endonuclease-mediated mutation 1, Jackson
• Allele ID: MGI:5784546
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Snapc2^em1(IMPC)J/Snapc2^em1(IMPC)J	C57BL/6NJ-Snapc2^em1(IMPC)J/J	MGI:6263542

Genotype
MGI:6263542

hm1

• Allelic Composition: Snapc2^em1(IMPC)J/Snapc2^em1(IMPC)J
• Genetic Background: C57BL/6NJ-Snapc2^em1(IMPC)J/J

Data Sources

IMPC Data for Snapc2

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cellular

increased cell death ( J:279207 )

• morulas recovered at E3.5 appear to be dying

• morulas show no further development with apparent cell death after 3 days in culture

embryo

failure of blastocyst formation ( J:279207 )

• embryos fail to reach a morphological blastocyst stage after 3 days in culture

failure of blastocyst to hatch from the zona pellucida ( J:279207 )

• in culture, embryos fail to hatch from the zona pellucida with apparent cell death, never reaching a morphological blastocyst stage

abnormal morula morphology ( J:279207 )

• morulas recovered at E3.5 appear to be dying

mortality/aging

embryonic lethality prior to organogenesis ( J:211773 )

IMPC - JAX

embryonic lethality before implantation, complete penetrance ( J:279207 )

• homozygous embryos are recovered at lower than expected Mendelian ratios at E3.5 (8% versus 25%) and appear to arrest/die prior to blastocyst formation; no embryos or excess resorption sites are observed at E7.5

preweaning lethality, complete penetrance ( J:211773 )

IMPC - JAX