Phenotypes associated with this allele

• Allele Symbol: Aldh1b1^tm1Vvas
• Allele Name: targeted mutation 1, Vasilis Vasiliou
• Allele ID: MGI:5779307
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Aldh1b1^tm1Vvas/Aldh1b1^tm1Vvas	B6J.Cg-Aldh1b1^tm1Vvas	MGI:5779315

Genotype
MGI:5779315

hm1

• Allelic Composition: Aldh1b1^tm1Vvas/Aldh1b1^tm1Vvas
• Genetic Background: B6J.Cg-Aldh1b1^tm1Vvas

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

homeostasis/metabolism

homeostasis/metabolism phenotype ( J:228677 )

N • in a glucose tolerance test, mice exhibit normal glucose tolerance

increased fasting circulating glucose level ( J:228677 )

abnormal xenobiotic pharmacokinetics ( J:228677 )

• following ethanol administration, mice exhibit decreased clearance of blood acetaldehyde compared with wild-type mice

endocrine/exocrine glands

endocrine/exocrine gland phenotype ( J:228677 )

N • mice exhibit normal insulin- and glucagon-positive cells in pancreatic islets