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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
SykM2Btlr
mutation 2, Bruce Beutler
MGI:5775011
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
SykM2Btlr/SykM2Btlr C57BL/6J-SykM2Btlr MGI:5775070
ht2
SykM2Btlr/Syk+ C57BL/6J-SykM2Btlr MGI:5775071


Genotype
MGI:5775070
hm1
Allelic
Composition
SykM2Btlr/SykM2Btlr
Genetic
Background
C57BL/6J-SykM2Btlr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
SykM2Btlr mutation (0 available); any Syk mutation (42 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
immune system
• increased frequencies of natural killer cells in the peripheral blood
• in response to priming with lipopolysaccharide (LPS) followed by nigericin treatment

hematopoietic system
• increased frequencies of natural killer cells in the peripheral blood




Genotype
MGI:5775071
ht2
Allelic
Composition
SykM2Btlr/Syk+
Genetic
Background
C57BL/6J-SykM2Btlr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
SykM2Btlr mutation (0 available); any Syk mutation (42 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
immune system
• increased frequencies of natural killer cells in the peripheral blood
• in response to priming with lipopolysaccharide (LPS) followed by nigericin treatment

hematopoietic system
• increased frequencies of natural killer cells in the peripheral blood





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory