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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Pitx2tm1b(EUCOMM)Wtsi
targeted mutation 1b, Wellcome Trust Sanger Institute
MGI:5760000
Summary 2 genotypes


Genotype
MGI:5767764
hm1
Allelic
Composition		 Pitx2tm1b(EUCOMM)Wtsi/Pitx2tm1b(EUCOMM)Wtsi
Genetic
Background		 C57BL/6N-Pitx2tm1b(EUCOMM)Wtsi/H
Cell Lines EPD0688_3_A07
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pitx2tm1b(EUCOMM)Wtsi mutation (0 available); any Pitx2 mutation (38 available)
Data Sources
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging




Genotype
MGI:5767763
ht2
Allelic
Composition		 Pitx2tm1b(EUCOMM)Wtsi/Pitx2+
Genetic
Background		 C57BL/6N-Pitx2tm1b(EUCOMM)Wtsi/H
Cell Lines EPD0688_3_A07
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pitx2tm1b(EUCOMM)Wtsi mutation (0 available); any Pitx2 mutation (38 available)
Data Sources
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological

cardiovascular system
enlarged heart ( J:211773 )
IMPC - HAR

craniofacial

endocrine/exocrine glands
small testis ( J:211773 )
IMPC - HAR

growth/size/body
enlarged heart ( J:211773 )
IMPC - HAR
abnormal tooth morphology ( J:211773 )
IMPC - HAR

nervous system

reproductive system
small testis ( J:211773 )
IMPC - HAR

skeleton

vision/eye
cornea opacity ( J:211773 )
IMPC - HAR




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
05/07/2024
MGI 6.23 		The Jackson Laboratory