Phenotypes associated with this allele

• Allele Symbol: Thoc6^em5(IMPC)Tcp
• Allele Name: endonuclease-mediated mutation 5, The Centre for Phenogenomics
• Allele ID: MGI:5755089
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Thoc6^em5(IMPC)Tcp/Thoc6^em5(IMPC)Tcp	C57BL/6NCrl-Thoc6^em5(IMPC)Tcp/Tcp	MGI:6263681
ht2	Thoc6^em5(IMPC)Tcp/Thoc6^+	C57BL/6NCrl-Thoc6^em5(IMPC)Tcp/Tcp	MGI:6263680

Genotype
MGI:6263681

hm1

• Allelic Composition: Thoc6^em5(IMPC)Tcp/Thoc6^em5(IMPC)Tcp
• Genetic Background: C57BL/6NCrl-Thoc6^em5(IMPC)Tcp/Tcp

Data Sources

IMPC Data for Thoc6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

embryo

embryonic growth retardation ( J:211773 )

IMPC - TCP

abnormal embryo size ( J:211773 )

IMPC - TCP

growth/size/body

embryonic growth retardation ( J:211773 )

IMPC - TCP

abnormal embryo size ( J:211773 )

IMPC - TCP

mortality/aging

embryonic lethality prior to tooth bud stage ( J:211773 )

IMPC - TCP

preweaning lethality, complete penetrance ( J:211773 )

IMPC - TCP

Genotype
MGI:6263680

ht2

• Allelic Composition: Thoc6^em5(IMPC)Tcp/Thoc6⁺
• Genetic Background: C57BL/6NCrl-Thoc6^em5(IMPC)Tcp/Tcp

Data Sources

IMPC Data for Thoc6

behavior/neurological

decreased exploration in new environment ( J:211773 )

IMPC - TCP

increased anxiety-related response ( J:211773 )

♂

IMPC - TCP

decreased vertical activity ( J:211773 )

♂

IMPC - TCP

decreased locomotor activity ( J:211773 )

♂

IMPC - TCP

cardiovascular system

shortened QRS complex duration ( J:211773 )

IMPC - TCP

endocrine/exocrine glands

enlarged ovary ( J:211773 )

♀

IMPC - TCP

growth/size/body

enlarged ovary ( J:211773 )

♀

IMPC - TCP

immune system

enlarged lymph nodes ( J:211773 )

♂

IMPC - TCP

reproductive system

enlarged ovary ( J:211773 )

♀

IMPC - TCP

respiratory system

abnormal lung morphology ( J:211773 )

♀

IMPC - TCP