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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tg(ITGAM-cre/ERT2,U6-RNAi:Cacna1b)17Ttan
transgene insertion 17, Tsutomu Tanabe
MGI:5705582
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
tg1
 		Tg(ITGAM-cre/ERT2,U6-RNAi:Cacna1b)17Ttan/0 C57BL/6J-Tg(ITGAM-cre/ERT2,U6-RNAi:Cacna1b)17Ttan MGI:5705592


Genotype
MGI:5705592
tg1
Allelic
Composition		 Tg(ITGAM-cre/ERT2,U6-RNAi:Cacna1b)17Ttan/0
Genetic
Background		 C57BL/6J-Tg(ITGAM-cre/ERT2,U6-RNAi:Cacna1b)17Ttan
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(ITGAM-cre/ERT2,U6-RNAi:Cacna1b)17Ttan mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
decreased susceptibility to injury ( J:221994 )
• following sciatic nerve ligation, tamoxifen-treated mice exhibit alleviated tactile allodynia and reduced accumulation of spinal microglia compared with control mice

behavior/neurological
behavior/neurological phenotype ( J:221994 )
N
• mice exhibit almost normal thermal hyperalgesia




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory