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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tg(Cdh5-cre/ERT2)#Ykub
transgene insertion, Yoshiaki Kubota
MGI:5705396
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Kdrtm2.1Jrt/Kdrtm2.1Jrt
Tg(Cdh5-cre/ERT2)#Ykub/0 		involves: 129S1/Sv * 129X1/SvJ MGI:5705501


Genotype
MGI:5705501
cn1
Allelic
Composition		 Kdrtm2.1Jrt/Kdrtm2.1Jrt
Tg(Cdh5-cre/ERT2)#Ykub/0
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Kdrtm2.1Jrt mutation (2 available); any Kdr mutation (67 available)
Tg(Cdh5-cre/ERT2)#Ykub mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
abnormal retina vasculature morphology ( J:217533 )
• impaired radial vascular growth
• however, no misdirected sprouting is observed in the neuroretina

vision/eye
abnormal retina vasculature morphology ( J:217533 )
• impaired radial vascular growth
• however, no misdirected sprouting is observed in the neuroretina




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory