All Phenotypes Tg(Cdh5-cre/ERT2)#Ykub MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Tg(Cdh5-cre/ERT2)#Ykub
transgene insertion, Yoshiaki Kubota
MGI:5705396

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Kdr^tm2.1Jrt/Kdr^tm2.1Jrt Tg(Cdh5-cre/ERT2)#Ykub/0	involves: 129S1/Sv * 129X1/SvJ	MGI:5705501

Allelic Composition	Kdr^tm2.1Jrt/Kdr^tm2.1Jrt Tg(Cdh5-cre/ERT2)#Ykub/0
Genetic Background	involves: 129S1/Sv * 129X1/SvJ

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Kdr^tm2.1Jrt mutation (2 available); any Kdr mutation (71 available)
Tg(Cdh5-cre/ERT2)#Ykub mutation (0 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

cardiovascular system

abnormal retina vasculature morphology ( J:217533 )

• impaired radial vascular growth

• however, no misdirected sprouting is observed in the neuroretina

vision/eye

abnormal retina vasculature morphology ( J:217533 )

• impaired radial vascular growth

• however, no misdirected sprouting is observed in the neuroretina

thin retina inner plexiform layer ( J:217533 )

decreased total retina thickness ( J:217533 )

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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