Tg(Cdh5-cre/ERT2)#Ykub
Transgene Detail

Summary

• Symbol: Tg(Cdh5-cre/ERT2)#Ykub
• Name: transgene insertion, Yoshiaki Kubota
• MGI ID: MGI:5705396
• Synonyms: VEcad-Cre^ERT2, VE-cadherin-CreER^T2
• Transgene: Tg(Cdh5-cre/ERT2)#Ykub Location: unknown
• Alliance: Tg(Cdh5-cre/ERT2)#Ykub page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Inducible, Recombinase)
• Inducer: tamoxifen
• Mutation: Insertion
• Tg(Cdh5-cre/ERT2)#Ykub expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Cdh5 (MGI:105057)

• Mutation details: The transgene was constructed from BAC clone RP23-453P1 to use the 200.3 kb mouse Cdh5 promoter to drive expression of an inducible cre recombinase gene (cre/ERT2). The pound symbol (#) is used when no line is specified and/or lines are pooled. (J:217533)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Cdh5 (mouse) Summary of all recombinase alleles driven by Cdh5. Comparative matrix view of recombinase activities Alliance mouse Cdh5 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:217533 Okabe K, et al., Neurons limit angiogenesis by titrating VEGF in retina. Cell. 2014 Oct 23;159(3):584-96
• All: 53 reference(s)