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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Ccl27atm1.1(KOMP)Vlcg
targeted mutation 1.1, Velocigene
MGI:5695899
Summary 2 genotypes


Genotype
MGI:7643496
hm1
Allelic
Composition		 Ccl27atm1.1(KOMP)Vlcg/Ccl27atm1.1(KOMP)Vlcg
Genetic
Background		 C57BL/6N-Ccl27atm1.1(KOMP)Vlcg/MbpMmucd
Cell Lines 14813A-F9
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ccl27atm1.1(KOMP)Vlcg mutation (1 available); any Ccl27a mutation (13 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
immune system phenotype ( J:330550 )
N
• adult mice show no significant differences in the percentages of CD4+, CD8+, or gamma-delta T cells in skin relative to wild-type or heterozygous controls
decreased regulatory T cell number ( J:330550 )
• adult mice show a marginal reduction of Treg cells in skin relative to wild-type or heterozygous controls

hematopoietic system
decreased regulatory T cell number ( J:330550 )
• adult mice show a marginal reduction of Treg cells in skin relative to wild-type or heterozygous controls




Genotype
MGI:7643504
cx2
Allelic
Composition		 Ccl27atm1.1(KOMP)Vlcg/Ccl27atm1.1(KOMP)Vlcg
Ccr10tm1.1Nax/Ccr10+
Genetic
Background		 B6.Cg-Ccl27atm1.1(KOMP)Vlcg Ccr10tm1.1Nax
Cell Lines 14813A-F9
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ccl27atm1.1(KOMP)Vlcg mutation (1 available); any Ccl27a mutation (13 available)
Ccr10tm1.1Nax mutation (0 available); any Ccr10 mutation (13 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
immune system phenotype ( J:330550 )
N
• adult mice show no significant differences in the percentages of CCR10(EGFP)+ Treg or other T cell subsets (CD4+, CD8+, and gamma-delta T cells) in skin relative to controls, indicating normal establishment of CCR10+ lymphocytes in adult skin




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory