Phenotypes associated with this allele

• Allele Symbol: Dhx16^{tm1b(EUCOMM)Wtsi}
• Allele Name: targeted mutation 1b, Wellcome Trust Sanger Institute
• Allele ID: MGI:5694174
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Dhx16^tm1b(EUCOMM)Wtsi/Dhx16^tm1b(EUCOMM)Wtsi	C57BL/6N-Dhx16^tm1b(EUCOMM)Wtsi/Bay	MGI:6262283
ht2	Dhx16^tm1b(EUCOMM)Wtsi/Dhx16^+	C57BL/6N-Dhx16^tm1b(EUCOMM)Wtsi/Bay	MGI:6288421

Genotype
MGI:6262283

hm1

• Allelic Composition: Dhx16^{tm1b(EUCOMM)Wtsi}/Dhx16^{tm1b(EUCOMM)Wtsi}
• Genetic Background: C57BL/6N-Dhx16^{tm1b(EUCOMM)Wtsi}/Bay
• Cell Lines: EPD0665_6_A04

Data Sources

IMPC Data for Dhx16

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality prior to organogenesis ( J:211773 )

IMPC - BCM

preweaning lethality, complete penetrance ( J:211773 )

IMPC - BCM

Genotype
MGI:6288421

ht2

• Allelic Composition: Dhx16^{tm1b(EUCOMM)Wtsi}/Dhx16⁺
• Genetic Background: C57BL/6N-Dhx16^{tm1b(EUCOMM)Wtsi}/Bay
• Cell Lines: EPD0665_6_A04

Data Sources

IMPC Data for Dhx16

behavior/neurological

decreased exploration in new environment ( J:211773 )

♀

IMPC - BCM

cardiovascular system

abnormal retina blood vessel morphology ( J:211773 )

IMPC - BCM

thick ventricular wall ( J:211773 )

♂

IMPC - BCM

vision/eye

abnormal retina blood vessel morphology ( J:211773 )

IMPC - BCM