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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Mcutm1c(EUCOMM)Hmgu
targeted mutation 1c, Helmholtz Zentrum Muenchen GmbH
MGI:5692853
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Mcutm1c(EUCOMM)Hmgu/Mcutm1c(EUCOMM)Hmgu
Tg(Pcp2-cre)2Mpin/0 		involves: 129S1/Sv * 129X1/SvJ * C57BL/6N MGI:6393522
cn2
 		Mcutm1c(EUCOMM)Hmgu/Mcutm1c(EUCOMM)Hmgu
Tg(Gabra6-cre)B1Lfr/0 		involves: C57BL/6N * DBA/2 MGI:6393523


Genotype
MGI:6393522
cn1
Allelic
Composition		 Mcutm1c(EUCOMM)Hmgu/Mcutm1c(EUCOMM)Hmgu
Tg(Pcp2-cre)2Mpin/0
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * C57BL/6N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mcutm1c(EUCOMM)Hmgu mutation (2 available); any Mcu mutation (27 available)
Tg(Pcp2-cre)2Mpin mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cellular
abnormal mitochondrial physiology ( J:281635 )
• reduced calcium buffering capacity in Purkinje cell mitochondria




Genotype
MGI:6393523
cn2
Allelic
Composition		 Mcutm1c(EUCOMM)Hmgu/Mcutm1c(EUCOMM)Hmgu
Tg(Gabra6-cre)B1Lfr/0
Genetic
Background		 involves: C57BL/6N * DBA/2
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mcutm1c(EUCOMM)Hmgu mutation (2 available); any Mcu mutation (27 available)
Tg(Gabra6-cre)B1Lfr mutation (2 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cellular
cellular phenotype ( J:281635 )
N
• normal calcium buffering capacity in granule cell mitochondria




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory