Phenotypes associated with this allele

• Allele Symbol: Tardbp^{tm1b(EUCOMM)Wtsi}
• Allele Name: targeted mutation 1b, Wellcome Trust Sanger Institute
• Allele ID: MGI:5692816
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Tardbp^tm1b(EUCOMM)Wtsi/Tardbp^tm1b(EUCOMM)Wtsi	C57BL/6N-Tardbp^tm1b(EUCOMM)Wtsi/H	MGI:5767821
ht2	Tardbp^tm1b(EUCOMM)Wtsi/Tardbp^+	C57BL/6N-Tardbp^tm1b(EUCOMM)Wtsi/H	MGI:5797852

Genotype
MGI:5767821

hm1

• Allelic Composition: Tardbp^{tm1b(EUCOMM)Wtsi}/Tardbp^{tm1b(EUCOMM)Wtsi}
• Genetic Background: C57BL/6N-Tardbp^{tm1b(EUCOMM)Wtsi}/H
• Cell Lines: EPD0828_4_C03

Data Sources

IMPC Data for Tardbp

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality prior to organogenesis ( J:211773 )

IMPC - HAR

preweaning lethality, complete penetrance ( J:211773 )

IMPC - HAR

Genotype
MGI:5797852

ht2

• Allelic Composition: Tardbp^{tm1b(EUCOMM)Wtsi}/Tardbp⁺
• Genetic Background: C57BL/6N-Tardbp^{tm1b(EUCOMM)Wtsi}/H
• Cell Lines: EPD0828_4_C03

Data Sources

IMPC Data for Tardbp

behavior/neurological

abnormal startle reflex ( J:211773 )

♂

IMPC - HAR

hematopoietic system

decreased mean platelet volume ( J:211773 )

♀

IMPC - HAR

homeostasis/metabolism

decreased blood urea nitrogen level ( J:211773 )

♀

IMPC - HAR

skeleton

decreased bone mineral content ( J:211773 )

♂

IMPC - HAR

decreased bone mineral density ( J:211773 )

♂

IMPC - HAR