Phenotypes associated with this allele

• Allele Symbol: Sdc4^{tm2b(KOMP)Wtsi}
• Allele Name: targeted mutation 2b, Wellcome Trust Sanger Institute
• Allele ID: MGI:5692630
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Sdc4^tm2b(KOMP)Wtsi/Sdc4^tm2b(KOMP)Wtsi	C57BL/6N-Sdc4^tm2b(KOMP)Wtsi/H	MGI:5797797
ht2	Sdc4^tm2b(KOMP)Wtsi/Sdc4^+	C57BL/6N-Sdc4^tm2b(KOMP)Wtsi/H	MGI:5797796

Genotype
MGI:5797797

hm1

• Allelic Composition: Sdc4^{tm2b(KOMP)Wtsi}/Sdc4^{tm2b(KOMP)Wtsi}
• Genetic Background: C57BL/6N-Sdc4^{tm2b(KOMP)Wtsi}/H
• Cell Lines: EPD0504_3_C10

Data Sources

IMPC Data for Sdc4

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

hematopoietic system

increased red blood cell distribution width ( J:211773 )

♂

IMPC - HAR

increased neutrophil cell number ( J:211773 )

♂

IMPC - HAR

decreased mean platelet volume ( J:211773 )

♀

IMPC - HAR

decreased lymphocyte cell number ( J:211773 )

♂

IMPC - HAR

homeostasis/metabolism

decreased circulating serum albumin level ( J:211773 )

♀

IMPC - HAR

decreased circulating total protein level ( J:211773 )

IMPC - HAR

immune system

increased neutrophil cell number ( J:211773 )

♂

IMPC - HAR

decreased lymphocyte cell number ( J:211773 )

♂

IMPC - HAR

Genotype
MGI:5797796

ht2

• Allelic Composition: Sdc4^{tm2b(KOMP)Wtsi}/Sdc4⁺
• Genetic Background: C57BL/6N-Sdc4^{tm2b(KOMP)Wtsi}/H
• Cell Lines: EPD0504_3_C10

Data Sources

IMPC Data for Sdc4

cardiovascular system

abnormal retina blood vessel morphology ( J:211773 )

IMPC - HAR

vision/eye

abnormal retina blood vessel morphology ( J:211773 )

IMPC - HAR

mydriasis ( J:211773 )

♂

IMPC - HAR