Phenotypes associated with this allele

• Allele Symbol: Ncoa5^{tm1.1(KOMP)Mbp}
• Allele Name: targeted mutation 1.1, Mouse Biology Program, UC Davis
• Allele ID: MGI:5637765
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Ncoa5^tm1.1(KOMP)Mbp/Ncoa5^tm1.1(KOMP)Mbp	C57BL/6N-Ncoa5^tm1.1(KOMP)Mbp/Tcp	MGI:6288599
ht2	Ncoa5^tm1.1(KOMP)Mbp/Ncoa5^+	C57BL/6N-Ncoa5^tm1.1(KOMP)Mbp/Tcp	MGI:6288598

Genotype
MGI:6288599

hm1

• Allelic Composition: Ncoa5^{tm1.1(KOMP)Mbp}/Ncoa5^{tm1.1(KOMP)Mbp}
• Genetic Background: C57BL/6N-Ncoa5^{tm1.1(KOMP)Mbp}/Tcp
• Cell Lines: DEPD00505_2_A04

Data Sources

IMPC Data for Ncoa5

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality prior to tooth bud stage ( J:211773 )

IMPC - TCP

embryonic lethality prior to organogenesis ( J:211773 )

IMPC - TCP

preweaning lethality, complete penetrance ( J:211773 )

IMPC - UCD

Genotype
MGI:6288598

ht2

• Allelic Composition: Ncoa5^{tm1.1(KOMP)Mbp}/Ncoa5⁺
• Genetic Background: C57BL/6N-Ncoa5^{tm1.1(KOMP)Mbp}/Tcp
• Cell Lines: DEPD00505_2_A04

Data Sources

IMPC Data for Ncoa5

cardiovascular system

abnormal heart morphology ( J:211773 )

♂

IMPC - UCD

enlarged heart ( J:211773 )

♂

IMPC - UCD

increased heart weight ( J:211773 )

♂

IMPC - UCD

growth/size/body

enlarged heart ( J:211773 )

♂

IMPC - UCD

increased heart weight ( J:211773 )

♂

IMPC - UCD

hematopoietic system

increased eosinophil cell number ( J:211773 )

♀

IMPC - UCD

immune system

increased eosinophil cell number ( J:211773 )

♀

IMPC - UCD

nervous system

small superior vagus ganglion ( J:211773 )

♀

IMPC - UCD

reproductive system

hydrometra ( J:211773 )

♀

IMPC - UCD