Phenotypes associated with this allele

• Allele Symbol: Tent5c^{tm1b(KOMP)Wtsi}
• Allele Name: targeted mutation 1b, Wellcome Trust Sanger Institute
• Allele ID: MGI:5637082
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Tent5c^tm1b(KOMP)Wtsi/Tent5c^tm1b(KOMP)Wtsi	C57BL/6N-Tent5c^tm1b(KOMP)Wtsi/Wtsi	MGI:5757084
ht2	Tent5c^tm1b(KOMP)Wtsi/Tent5c^+	C57BL/6N-Tent5c^tm1b(KOMP)Wtsi/Wtsi	MGI:5757083

Genotype
MGI:5757084

hm1

• Allelic Composition: Tent5c^{tm1b(KOMP)Wtsi}/Tent5c^{tm1b(KOMP)Wtsi}
• Genetic Background: C57BL/6N-Tent5c^{tm1b(KOMP)Wtsi}/Wtsi
• Cell Lines: EPD0824_2_A02

Data Sources

IMPC Data for Tent5c

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

abnormal vertebral artery topology ( J:239583 )

DMDD

additional anastomosis between intracranial vertebral arteries ( J:239583 )

DMDD

absent ductus venosus valve ( J:239583 )

DMDD

abnormal hepatic vein morphology ( J:239583 )

DMDD

dual inferior vena cava ( J:239583 )

DMDD

muscular ventricular septal defect ( J:239583 )

DMDD

hemorrhage ( J:239583 )

DMDD

craniofacial

cleft palate ( J:239583 )

DMDD

digestive/alimentary system

cleft palate ( J:239583 )

DMDD

abnormal small intestine placement ( J:239583 )

DMDD

embryo

abnormal Mullerian duct morphology ( J:239583 )

DMDD

endocrine/exocrine glands

abnormal bile duct morphology ( J:239583 )

DMDD

growth/size/body

cleft palate ( J:239583 )

DMDD

homeostasis/metabolism

subcutaneous edema ( J:239583 )

DMDD

immune system

absent connection between subcutaneous lymph vessels and lymph sac ( J:239583 )

DMDD

blood in lymph vessels ( J:239583 )

DMDD

integument

subcutaneous edema ( J:239583 )

DMDD

liver/biliary system

abnormal bile duct morphology ( J:239583 )

DMDD

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - WTSI

nervous system

abnormal forebrain morphology ( J:239583 )

DMDD

renal/urinary system

small kidney ( J:239583 )

DMDD

skeleton

fusion of vertebral arches ( J:239583 )

DMDD

Genotype
MGI:5757083

ht2

• Allelic Composition: Tent5c^{tm1b(KOMP)Wtsi}/Tent5c⁺
• Genetic Background: C57BL/6N-Tent5c^{tm1b(KOMP)Wtsi}/Wtsi
• Cell Lines: EPD0824_2_A02

Data Sources

IMPC Data for Tent5c

behavior/neurological

increased grip strength ( J:211773 )

♀

IMPC - WTSI

hematopoietic system

decreased mean corpuscular hemoglobin ( J:211773 )

IMPC - WTSI