All Phenotypes Nrxn1<tm1b(KOMP)Wtsi> MGI Mouse

About Help FAQ

Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Nrxn1^{tm1b(KOMP)Wtsi}
targeted mutation 1b, Wellcome Trust Sanger Institute
MGI:5636923

Summary

2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Nrxn1^{tm1b(KOMP)Wtsi}/Nrxn1^{tm1b(KOMP)Wtsi}	C57BL/6N-Nrxn1^{tm1b(KOMP)Wtsi}/H	MGI:5757433
ht2	Nrxn1^{tm1b(KOMP)Wtsi}/Nrxn1⁺	C57BL/6N-Nrxn1^{tm1b(KOMP)Wtsi}/H	MGI:5797687

Allelic Composition	Nrxn1^{tm1b(KOMP)Wtsi}/Nrxn1^{tm1b(KOMP)Wtsi}
Genetic Background	C57BL/6N-Nrxn1^{tm1b(KOMP)Wtsi}/H
Cell Lines	EPD0796_5_E08

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nrxn1^{tm1b(KOMP)Wtsi} mutation (0 available); any Nrxn1 mutation (95 available)

Data Sources

IMPC Data for Nrxn1

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

adipose tissue

decreased total body fat amount ( J:211773 )

IMPC - HAR

behavior/neurological

tremors ( J:211773 )

IMPC - HAR

decreased grip strength ( J:211773 )

IMPC - HAR

homeostasis/metabolism

decreased fasting circulating glucose level ( J:211773 )

IMPC - HAR

decreased circulating cholesterol level ( J:211773 )

IMPC - HAR

decreased circulating HDL cholesterol level ( J:211773 )

IMPC - HAR

decreased circulating alkaline phosphatase level ( J:211773 )

IMPC - HAR

increased circulating aspartate transaminase level ( J:211773 )

IMPC - HAR

decreased circulating serum albumin level ( J:211773 )

IMPC - HAR

decreased circulating total protein level ( J:211773 )

IMPC - HAR

impaired glucose tolerance ( J:211773 )

IMPC - HAR

respiratory system

decreased pulmonary respiratory rate ( J:211773 )

IMPC - HAR

skeleton

abnormal bone structure ( J:211773 )

IMPC - HAR

Allelic Composition	Nrxn1^{tm1b(KOMP)Wtsi}/Nrxn1⁺
Genetic Background	C57BL/6N-Nrxn1^{tm1b(KOMP)Wtsi}/H
Cell Lines	EPD0796_5_E08

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nrxn1^{tm1b(KOMP)Wtsi} mutation (0 available); any Nrxn1 mutation (95 available)

Data Sources

IMPC Data for Nrxn1

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

tremors ( J:211773 )

IMPC - HAR

digestive/alimentary system

enlarged stomach ( J:211773 )

IMPC - HAR

endocrine/exocrine glands

small thymus ( J:211773 )

IMPC - HAR

growth/size/body

increased lean body mass ( J:211773 )

IMPC - HAR

hematopoietic system

small thymus ( J:211773 )

IMPC - HAR

homeostasis/metabolism

increased circulating amylase level ( J:211773 )

IMPC - HAR

immune system

small thymus ( J:211773 )

IMPC - HAR

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 05/07/2024 MGI 6.23