All Phenotypes Pdia4<tm1b(EUCOMM)Wtsi> MGI Mouse

About Help FAQ

Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Pdia4^{tm1b(EUCOMM)Wtsi}
targeted mutation 1b, Wellcome Trust Sanger Institute
MGI:5636896

Summary

3 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Pdia4^{tm1b(EUCOMM)Wtsi}/Pdia4^{tm1b(EUCOMM)Wtsi}	C57BL/6N-Pdia4^{tm1b(EUCOMM)Wtsi}/Wtsi	MGI:6263125
cn2	Pdia4^{tm1b(EUCOMM)Wtsi}/Pdia4^{tm1b(EUCOMM)Wtsi} Tg(Tek-cre)12Flv/0	involves: C3H * C57BL/6N	MGI:6157438
cn3	Pdia4^{tm1b(EUCOMM)Wtsi}/Pdia4^{tm1b(EUCOMM)Wtsi} Tg(Pf4-icre)Q3Rsko/0	involves: C57BL/6N	MGI:6157437

Allelic Composition	Pdia4^{tm1b(EUCOMM)Wtsi}/Pdia4^{tm1b(EUCOMM)Wtsi}
Genetic Background	C57BL/6N-Pdia4^{tm1b(EUCOMM)Wtsi}/Wtsi
Cell Lines	EPD0629_2_A03

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pdia4^{tm1b(EUCOMM)Wtsi} mutation (1 available); any Pdia4 mutation (43 available)

Data Sources

IMPC Data for Pdia4

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

homeostasis/metabolism

increased circulating aspartate transaminase level ( J:211773 )

IMPC - WTSI

increased circulating creatine kinase level ( J:211773 )

IMPC - WTSI

Allelic Composition	Pdia4^{tm1b(EUCOMM)Wtsi}/Pdia4^{tm1b(EUCOMM)Wtsi} Tg(Tek-cre)12Flv/0
Genetic Background	involves: C3H * C57BL/6N

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pdia4^{tm1b(EUCOMM)Wtsi} mutation (1 available); any Pdia4 mutation (43 available)
Tg(Tek-cre)12Flv mutation (1 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

hematopoietic system

hematopoietic system phenotype ( J:244748 )

N	• mice exhibit normal platelet counts and size, prothrombin time, partial thromboplastin time, and fibrinogen levels

decreased platelet aggregation ( J:244748 )

homeostasis/metabolism

decreased platelet aggregation ( J:244748 )

increased bleeding time ( J:244748 )

Allelic Composition	Pdia4^{tm1b(EUCOMM)Wtsi}/Pdia4^{tm1b(EUCOMM)Wtsi} Tg(Pf4-icre)Q3Rsko/0
Genetic Background	involves: C57BL/6N

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pdia4^{tm1b(EUCOMM)Wtsi} mutation (1 available); any Pdia4 mutation (43 available)
Tg(Pf4-icre)Q3Rsko mutation (1 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

hematopoietic system

hematopoietic system phenotype ( J:244748 )

N	• mice exhibit normal platelet counts and size and fibrin deposition

decreased platelet ATP level ( J:244748 )

decreased platelet aggregation ( J:244748 )

• induced by thrombin, convulxin or ADP

homeostasis/metabolism

decreased platelet ATP level ( J:244748 )

decreased platelet aggregation ( J:244748 )

• induced by thrombin, convulxin or ADP

cellular

decreased platelet ATP level ( J:244748 )

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/30/2024 MGI 6.23