Phenotypes associated with this allele

• Allele Symbol: Cyb561^{tm1b(EUCOMM)Wtsi}
• Allele Name: targeted mutation 1b, Wellcome Trust Sanger Institute
• Allele ID: MGI:5636891
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Cyb561^tm1b(EUCOMM)Wtsi/Cyb561^tm1b(EUCOMM)Wtsi	C57BL/6N-Cyb561^tm1b(EUCOMM)Wtsi/H	MGI:5756935

Genotype
MGI:5756935

hm1

• Allelic Composition: Cyb561^{tm1b(EUCOMM)Wtsi}/Cyb561^{tm1b(EUCOMM)Wtsi}
• Genetic Background: C57BL/6N-Cyb561^{tm1b(EUCOMM)Wtsi}/H
• Cell Lines: EPD0037_3_G01

Data Sources

IMPC Data for Cyb561

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

adipose tissue

increased total body fat amount ( J:211773 )

IMPC - HAR

behavior/neurological

decreased exploration in new environment ( J:211773 )

♀

IMPC - HAR

tremors ( J:211773 )

IMPC - HAR

abnormal gait ( J:211773 )

♂

IMPC - HAR

cardiovascular system

abnormal retina blood vessel morphology ( J:211773 )

♂

IMPC - HAR

enlarged heart ( J:211773 )

♂

IMPC - HAR

craniofacial

abnormal cranium morphology ( J:211773 )

IMPC - HAR

abnormal maxilla morphology ( J:211773 )

IMPC - HAR

abnormal snout morphology ( J:211773 )

♀

IMPC - HAR

growth/size/body

enlarged heart ( J:211773 )

♂

IMPC - HAR

abnormal snout morphology ( J:211773 )

♀

IMPC - HAR

decreased lean body mass ( J:211773 )

IMPC - HAR

abnormal head size ( J:211773 )

IMPC - HAR

homeostasis/metabolism

decreased circulating glucose level ( J:211773 )

♂

IMPC - HAR

decreased fasting circulating glucose level ( J:211773 )

IMPC - HAR

increased circulating triglyceride level ( J:211773 )

♀

IMPC - HAR

increased circulating alkaline phosphatase level ( J:211773 )

♀

IMPC - HAR

increased circulating amylase level ( J:211773 )

♀

IMPC - HAR

increased circulating aspartate transaminase level ( J:211773 )

♀

IMPC - HAR

decreased circulating serum albumin level ( J:211773 )

IMPC - HAR

decreased circulating total protein level ( J:211773 )

♂

IMPC - HAR

limbs/digits/tail

abnormal tail length ( J:211773 )

IMPC - HAR

skeleton

abnormal cranium morphology ( J:211773 )

IMPC - HAR

abnormal maxilla morphology ( J:211773 )

IMPC - HAR

abnormal bone structure ( J:211773 )

♀

IMPC - HAR

decreased bone mineral content ( J:211773 )

IMPC - HAR

vision/eye

abnormal retina blood vessel morphology ( J:211773 )

♂

IMPC - HAR

abnormal iris morphology ( J:211773 )

♂

IMPC - HAR

narrow eye opening ( J:211773 )

♂

IMPC - HAR