Phenotypes associated with this allele
|
|
| Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sortm1(GRN)Pvd mutation
(0 available);
any
Gt(ROSA)26Sor mutation
(942 available)
Tg(Pgk1-cre)1Lni mutation
(1 available)
Tg(SOD1*G93A)1Gur mutation
(4 available)
|
|
|
mortality/aging
|
|
• average lifespan is 163.3 days
|
nervous system
|
|
• onset or progression of motor neuron degeneration is similar to that seen in mice expressing only Tg(SOD1*G93A)1Gur, with an average onset of disease at 134.2 days
|
behavior/neurological
|
|
• mice show impaired performance on the rotarod and in hanging from a grid to a similar extent as seen in mice expressing only Tg(SOD1*G93A)1Gur
|
|
|
| Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sortm1(GRN)Pvd mutation
(0 available);
any
Gt(ROSA)26Sor mutation
(942 available)
Tg(Pgk1-cre)1Lni mutation
(1 available)
Tg(SOD1*G93A)1Gur mutation
(4 available)
|
|
|
mortality/aging
|
|
• average lifespan is 168.4 days
|
nervous system
|
|
• onset or progression of motor neuron degeneration is similar to that seen in mice expressing only Tg(SOD1*G93A)1Gur, with an average onset of disease at 138.2 days
|
behavior/neurological
|
|
• mice show impaired performance on the rotarod and in hanging from a grid to a similar extent as seen in mice expressing only Tg(SOD1*G93A)1Gur
|
Analysis Tools