Analysis Tools|
Allele Symbol Allele Name Allele ID |
Tg(HLA-DRA,HLA-DRB5*0101)loKito transgene insertion lo, Kouichi Ito MGI:5635431 |
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| Summary |
2 genotypes
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• mice develop spontaneous experimental autoimmune encephalitis with an incidence of 5%; onset of disease is around 12 weeks of age
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• mice develop spontaneous experimental autoimmune encephalitis with an incidence of 5%; onset of disease is around 12 weeks of age
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• mice rarely exhibit experimental autoimmune encephalitis when immunized with CFA or pertussis alone, but immunization with MBP (83-99) in CFA with pertussis elicits encephalitis in 47% of mice
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• mice develop spontaneous autoimmune encephalitis with an incidence of <1%; onset of disease is around 21 weeks of age
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• mice develop spontaneous autoimmune encephalitis with an incidence of <1%; onset of disease is around 21 weeks of age
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 09/30/2025 MGI 6.24 |
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