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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Il22tm1.1(icre)Stck
targeted mutation 1.1, Brigitta Stockinger
MGI:5632146
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cn1
Il22tm1.1(icre)Stck/Il22tm1.1(icre)Stck involves: 129X1/SvJ * C57BL/6N MGI:5634194
cn2
Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+
Il22tm1.1(icre)Stck/Il22+
involves: 129X1/SvJ * C57BL/6N MGI:5634193


Genotype
MGI:5634194
cn1
Allelic
Composition
Il22tm1.1(icre)Stck/Il22tm1.1(icre)Stck
Genetic
Background
involves: 129X1/SvJ * C57BL/6N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Il22tm1.1(icre)Stck mutation (1 available); any Il22 mutation (27 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
immune system
• mice infected with Citrobacter exhibit expanded infection and fail to control Citrobacter compared with control mice




Genotype
MGI:5634193
cn2
Allelic
Composition
Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+
Il22tm1.1(icre)Stck/Il22+
Genetic
Background
involves: 129X1/SvJ * C57BL/6N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sortm1(EYFP)Cos mutation (11 available); any Gt(ROSA)26Sor mutation (944 available)
Il22tm1.1(icre)Stck mutation (1 available); any Il22 mutation (27 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
immune system
• mice infected with Citrobacter exhibit increased transient weight loss compared with wild-type mice and mice heterozygous for a knock-out allele
• however, mice exhibit normal clearance and kinetics of infection

growth/size/body
• mice infected with Citrobacter exhibit increased transient weight loss compared with wild-type mice and mice heterozygous for a knock-out allele
• however, mice exhibit normal clearance and kinetics of infection





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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory