About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Nxf1em1Haml
endonuclease-mediated mutation 1, Bruce Hamilton
MGI:5629959
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cx1
 		Nxf1em1Haml/Nxf1Mvb1
Pitpnavb/Pitpnavb 		involves: C57BL/6 * DBA/2J MGI:5629975
cx2
 		Nxf1em1Haml/Nxf1+
Pitpnavb/Pitpnavb 		involves: C57BL/6J * DBA/2J MGI:5629974


Genotype
MGI:5629975
cx1
Allelic
Composition		 Nxf1em1Haml/Nxf1Mvb1
Pitpnavb/Pitpnavb
Genetic
Background		 involves: C57BL/6 * DBA/2J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nxf1em1Haml mutation (1 available); any Nxf1 mutation (35 available)
Nxf1Mvb1 mutation (1 available); any Nxf1 mutation (35 available)
Pitpnavb mutation (1 available); any Pitpna mutation (37 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
abnormal survival ( J:219914 )
• improved survival compared with Nxf1Mvb1-C57BL/6J/Nxf1Mvb1-CAST/Ei Pitpnavb/Pitpnavb mice

behavior/neurological
tremors ( J:219914 )
• reduced tremor score compared with Nxf1Mvb1-C57BL/6J/Nxf1Mvb1-CAST/Ei Pitpnavb/Pitpnavb mice




Genotype
MGI:5629974
cx2
Allelic
Composition		 Nxf1em1Haml/Nxf1+
Pitpnavb/Pitpnavb
Genetic
Background		 involves: C57BL/6J * DBA/2J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nxf1em1Haml mutation (1 available); any Nxf1 mutation (35 available)
Pitpnavb mutation (1 available); any Pitpna mutation (37 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
abnormal survival ( J:219914 )
• improved survival compared with Nxf1Mvb1-C57BL/6J Pitpnavb double homozygotes

behavior/neurological
tremors ( J:219914 )
• reduced tremor score compared with Nxf1Mvb1-C57BL/6J Pitpnavb double homozygotes




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory