Phenotypes associated with this allele

• Allele Symbol: Nxn^em1(IMPC)J
• Allele Name: endonuclease-mediated mutation 1, Jackson
• Allele ID: MGI:5620177
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Nxn^em1(IMPC)J/Nxn^em1(IMPC)J	C57BL/6NJ-Nxn^em1(IMPC)J/J	MGI:5884018
ht2	Nxn^em1(IMPC)J/Nxn^+	C57BL/6NJ-Nxn^em1(IMPC)J/J	MGI:6263064

Genotype
MGI:5884018

hm1

• Allelic Composition: Nxn^em1(IMPC)J/Nxn^em1(IMPC)J
• Genetic Background: C57BL/6NJ-Nxn^em1(IMPC)J/J

Data Sources

IMPC Data for Nxn

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

craniofacial

abnormal facial morphology ( J:211773 )

IMPC - JAX

cleft palate ( J:211773 )

IMPC - JAX

facial cleft ( J:211773 )

♂

IMPC - JAX

digestive/alimentary system

cleft palate ( J:211773 )

IMPC - JAX

embryo

abnormal embryo size ( J:211773 )

IMPC - JAX

growth/size/body

abnormal facial morphology ( J:211773 )

IMPC - JAX

cleft palate ( J:211773 )

IMPC - JAX

facial cleft ( J:211773 )

♂

IMPC - JAX

abnormal embryo size ( J:211773 )

IMPC - JAX

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - JAX

Genotype
MGI:6263064

ht2

• Allelic Composition: Nxn^em1(IMPC)J/Nxn⁺
• Genetic Background: C57BL/6NJ-Nxn^em1(IMPC)J/J

Data Sources

IMPC Data for Nxn

hematopoietic system

increased mean corpuscular hemoglobin concentration ( J:211773 )

♀

IMPC - JAX

homeostasis/metabolism

increased fasting circulating glucose level ( J:211773 )

IMPC - JAX