Analysis Tools
embryo
| N |
• spinal cord development proceeds without significant defects
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Allele Symbol Allele Name Allele ID |
Sox2tm1.1Knd targeted mutation 1.1, Hisato Kondoh MGI:5613017 |
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| Summary |
2 genotypes
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
| N |
• spinal cord development proceeds without significant defects
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• absence of genes associated with neural tube development in the paraxial compartment concomitant with absence of tubular structures at E9.5
• expression analysis indicates absence of markers for the paraxial mesoderm, intermediate mesoderm and endoderm
• however, unlike mice homozygous for the Tbx6 mutation alone, no ectopic expression of Sox2 is seen in the neural tube
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• absence of genes associated with neural tube development in the paraxial compartment concomitant with absence of tubular structures at E9.5
• expression analysis indicates absence of markers for the paraxial mesoderm, intermediate mesoderm and endoderm
• however, unlike mice homozygous for the Tbx6 mutation alone, no ectopic expression of Sox2 is seen in the neural tube
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/07/2024 MGI 6.23 |
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