All Phenotypes Lepr<m6Btlr> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Lepr^m6Btlr
mutation 6, Bruce Beutler
MGI:5609704

Summary

2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Lepr^m6Btlr/Lepr^m6Btlr	C57BL/6J-Lepr^m6Btlr	MGI:5609706
ht2	Lepr^m6Btlr/Lepr⁺	C57BL/6J-Lepr^m6Btlr	MGI:5609711

Allelic Composition	Lepr^m6Btlr/Lepr^m6Btlr
Genetic Background	C57BL/6J-Lepr^m6Btlr

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lepr^m6Btlr mutation (0 available); any Lepr mutation (121 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

growth/size/body

increased body weight ( J:216794 )

• mice homozygous for this mutation exhibit a significant increase in body weight compared to wild-type mice.

Allelic Composition	Lepr^m6Btlr/Lepr⁺
Genetic Background	C57BL/6J-Lepr^m6Btlr

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lepr^m6Btlr mutation (0 available); any Lepr mutation (121 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

growth/size/body

increased body weight ( J:216794 )

• mice heterozygous for this mutation exhibit a significantly increased body weight, intermediate between those of homozyous mutant and and wild-type mice, but not significant enough to consider the allele semidominant.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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