Phenotypes associated with this allele

• Allele Symbol: Smarcb1^{tm1b(EUCOMM)Hmgu}
• Allele Name: targeted mutation 1b, Helmholtz Zentrum Muenchen GmbH
• Allele ID: MGI:5609344
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Smarcb1^tm1b(EUCOMM)Hmgu/Smarcb1^tm1b(EUCOMM)Hmgu	C57BL/6N-Smarcb1^tm1b(EUCOMM)Hmgu/Bay	MGI:6263519
ht2	Smarcb1^tm1b(EUCOMM)Hmgu/Smarcb1^+	C57BL/6N-Smarcb1^tm1b(EUCOMM)Hmgu/Bay	MGI:6288735

Genotype
MGI:6263519

hm1

• Allelic Composition: Smarcb1^{tm1b(EUCOMM)Hmgu}/Smarcb1^{tm1b(EUCOMM)Hmgu}
• Genetic Background: C57BL/6N-Smarcb1^{tm1b(EUCOMM)Hmgu}/Bay
• Cell Lines: HEPD0744_6_B09

Data Sources

IMPC Data for Smarcb1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality prior to organogenesis ( J:211773 )

IMPC - BCM

preweaning lethality, complete penetrance ( J:211773 )

IMPC - BCM

Genotype
MGI:6288735

ht2

• Allelic Composition: Smarcb1^{tm1b(EUCOMM)Hmgu}/Smarcb1⁺
• Genetic Background: C57BL/6N-Smarcb1^{tm1b(EUCOMM)Hmgu}/Bay
• Cell Lines: HEPD0744_6_B09

Data Sources

IMPC Data for Smarcb1

integument

abnormal coat appearance ( J:211773 )

♂

IMPC - BCM

abnormal skin coloration ( J:211773 )

IMPC - BCM

nervous system

decreased prepulse inhibition ( J:211773 )

♀

IMPC - BCM

vision/eye

increased cornea thickness ( J:211773 )

IMPC - BCM

abnormal eye anterior chamber depth ( J:211773 )

♀

IMPC - BCM