All Phenotypes Zfp318<tm1.1Jhws> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Zfp318^tm1.1Jhws
targeted mutation 1.1, John Weis
MGI:5606279

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Zfp318^tm1.1Jhws/Zfp318^tm1.1Jhws Commd10^{Tg(Vav1-icre)A2Kio}/Commd10⁺	B6.Cg-Zfp318^tm1.1Jhws Tg^Vav1-creA2Kio	MGI:5606282

Allelic Composition	Zfp318^tm1.1Jhws/Zfp318^tm1.1Jhws Commd10^{Tg(Vav1-icre)A2Kio}/Commd10⁺
Genetic Background	B6.Cg-Zfp318^tm1.1Jhws Tg^Vav1-creA2Kio

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Commd10^{Tg(Vav1-icre)A2Kio} mutation (3 available); any Commd10 mutation (24 available)
Zfp318^tm1.1Jhws mutation (1 available); any Zfp318 mutation (80 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

immune system

decreased transitional stage T2 B cell number ( J:215815 )

• slight decrease in splenic T2 B cells in 4 week old mice

decreased IgD level ( J:215815 )

• decreased levels of IgD in transitional type 1 and 2 (T1,2), follicular (FO) and marginal zone (MZ) B cell populations

increased IgM level ( J:215815 )

• increased levels of IgM in transitional type 2 (T2), follicular (FO) and marginal zone (MZ) B cell populations

hematopoietic system