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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Atg16l1tm2.1Mvlc
targeted mutation 2.1, Menno van Lookeren Campagne
MGI:5605965
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Atg16l1tm2.1Mvlc/Atg16l1tm2.1Mvlc
Lyz2tm1(cre)Ifo/Lyz2+ 		involves: 129P2/OlaHsd * C57BL/6 MGI:5605967


Genotype
MGI:5605967
cn1
Allelic
Composition		 Atg16l1tm2.1Mvlc/Atg16l1tm2.1Mvlc
Lyz2tm1(cre)Ifo/Lyz2+
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Atg16l1tm2.1Mvlc mutation (0 available); any Atg16l1 mutation (46 available)
Lyz2tm1(cre)Ifo mutation (16 available); any Lyz2 mutation (40 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cellular
impaired autophagy ( J:206931 )
• defect in autophagy in nutrient starved macrophages

homeostasis/metabolism
impaired autophagy ( J:206931 )
• defect in autophagy in nutrient starved macrophages




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory