Phenotypes associated with this allele

• Allele Symbol: Cecr2^{tm2b(EUCOMM)Hmgu}
• Allele Name: targeted mutation 2b, Helmholtz Zentrum Muenchen GmbH
• Allele ID: MGI:5605798
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Cecr2^tm2b(EUCOMM)Hmgu/Cecr2^tm2b(EUCOMM)Hmgu	C57BL/6N-Cecr2^tm2b(EUCOMM)Hmgu/Tcp	MGI:5767595
ht2	Cecr2^tm2b(EUCOMM)Hmgu/Cecr2^+	C57BL/6N-Cecr2^tm2b(EUCOMM)Hmgu/Tcp	MGI:5797432

Genotype
MGI:5767595

hm1

• Allelic Composition: Cecr2^{tm2b(EUCOMM)Hmgu}/Cecr2^{tm2b(EUCOMM)Hmgu}
• Genetic Background: C57BL/6N-Cecr2^{tm2b(EUCOMM)Hmgu}/Tcp
• Cell Lines: HEPD0805_1_C08

Data Sources

IMPC Data for Cecr2

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

craniofacial

abnormal craniofacial morphology ( J:211773 )

IMPC - TCP

embryo

abnormal neural tube closure ( J:211773 )

♀

IMPC - TCP

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - TCP

nervous system

abnormal neural tube closure ( J:211773 )

♀

IMPC - TCP

abnormal midbrain morphology ( J:211773 )

♀

IMPC - TCP

abnormal forebrain morphology ( J:211773 )

♀

IMPC - TCP

abnormal hindbrain morphology ( J:211773 )

♀

IMPC - TCP

Genotype
MGI:5797432

ht2

• Allelic Composition: Cecr2^{tm2b(EUCOMM)Hmgu}/Cecr2⁺
• Genetic Background: C57BL/6N-Cecr2^{tm2b(EUCOMM)Hmgu}/Tcp
• Cell Lines: HEPD0805_1_C08

Data Sources

IMPC Data for Cecr2

behavior/neurological

decreased exploration in new environment ( J:211773 )

♀

IMPC - TCP

cardiovascular system

abnormal QT variability ( J:211773 )

♀

IMPC - TCP

embryo

abnormal neural tube closure ( J:211773 )

IMPC - TCP

homeostasis/metabolism

increased circulating alkaline phosphatase level ( J:211773 )

IMPC - TCP

immune system

enlarged lymph nodes ( J:211773 )

♀

IMPC - TCP

nervous system

abnormal neural tube closure ( J:211773 )

IMPC - TCP

abnormal midbrain morphology ( J:211773 )

IMPC - TCP

abnormal forebrain morphology ( J:211773 )

IMPC - TCP

abnormal hindbrain morphology ( J:211773 )

IMPC - TCP