Phenotypes associated with this allele
|
|
| Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ticam2M1Btlr mutation
(1 available);
any
Ticam2 mutation
(21 available)
|
|
|
immune system
|
|
• mice with this mutation exhibit diminished secretion of tumor necrosis factor alpha (TNFalpha) in response to the Toll-like receptor 4 (TLR4) ligand, lipopolysaccharide (LPS); TNFalpha secretion by heterozygous mutant mice is intermediate between that of homozygous mutant and wild-type control mice.
|
|
|
| Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ticam2M1Btlr mutation
(1 available);
any
Ticam2 mutation
(21 available)
|
|
|
immune system
|
|
• mice with this mutation exhibit diminished secretion of tumor necrosis factor alpha (TNFalpha) in response to the Toll-like receptor 4 (TLR4) ligand, lipopolysaccharide (LPS); TNFalpha secretion by heterozygous mutant mice is intermediate between that of homozygous mutant and wild-type control mice.
|
Analysis Tools