Phenotypes associated with this allele

• Allele Symbol: Klk5^{tm2b(KOMP)Wtsi}
• Allele Name: targeted mutation 2b, Wellcome Trust Sanger Institute
• Allele ID: MGI:5604101
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Klk5^tm2b(KOMP)Wtsi/Klk5^tm2b(KOMP)Wtsi	C57BL/6N-Klk5^tm2b(KOMP)Wtsi/Ccpcz	MGI:6317427

Genotype
MGI:6317427

hm1

• Allelic Composition: Klk5^{tm2b(KOMP)Wtsi}/Klk5^{tm2b(KOMP)Wtsi}
• Genetic Background: C57BL/6N-Klk5^{tm2b(KOMP)Wtsi}/Ccpcz
• Cell Lines: EPD0151_6_H11

Data Sources

IMPC Data for Klk5

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

decreased startle reflex ( J:211773 )

IMPC - HMGU

decreased locomotor activity ( J:211773 )

IMPC - HMGU

cardiovascular system

abnormal retina vasculature morphology ( J:211773 )

♀

IMPC - HMGU

abnormal retina blood vessel morphology ( J:211773 )

♀

IMPC - HMGU

hearing/vestibular/ear

abnormal auditory brainstem response ( J:211773 )

IMPC - HMGU

hematopoietic system

decreased mean corpuscular hemoglobin concentration ( J:211773 )

IMPC - HMGU

increased red blood cell distribution width ( J:211773 )

♀

IMPC - HMGU

homeostasis/metabolism

increased circulating phosphate level ( J:211773 )

♀

IMPC - HMGU

limbs/digits/tail

long tibia ( J:211773 )

IMPC - HMGU

skeleton

long tibia ( J:211773 )

IMPC - HMGU

vision/eye

abnormal retina morphology ( J:211773 )

♂

IMPC - HMGU

abnormal retina vasculature morphology ( J:211773 )

♀

IMPC - HMGU

abnormal retina blood vessel morphology ( J:211773 )

♀

IMPC - HMGU

decreased total retina thickness ( J:211773 )

IMPC - HMGU

abnormal vitreous body morphology ( J:211773 )

IMPC - HMGU