All Phenotypes Yap1<tm1c(KOMP)Mbp> MGI Mouse

About Help FAQ

Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Yap1^{tm1c(KOMP)Mbp}
targeted mutation 1c, Mouse Biology Program, UC Davis
MGI:5603606

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Mob1a^tm1.1Asuz/Mob1a^tm1.1Asuz Mob1b^{Gt(CC0690)Wtsi}/Mob1b^{Gt(CC0690)Wtsi} Yap1^{tm1c(KOMP)Mbp}/Yap1^{tm1c(KOMP)Mbp} Speer6-ps1^{Tg(Alb-cre)21Mgn}/Speer6-ps1⁺	involves: 129P2/OlaHsd * C57BL/6 * C57BL/6N * DBA	MGI:5897815

Allelic Composition	Mob1a^tm1.1Asuz/Mob1a^tm1.1Asuz Mob1b^{Gt(CC0690)Wtsi}/Mob1b^{Gt(CC0690)Wtsi} Yap1^{tm1c(KOMP)Mbp}/Yap1^{tm1c(KOMP)Mbp} Speer6-ps1^{Tg(Alb-cre)21Mgn}/Speer6-ps1⁺
Genetic Background	involves: 129P2/OlaHsd * C57BL/6 * C57BL/6N * DBA

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mob1a^tm1.1Asuz mutation (0 available); any Mob1a mutation (18 available)
Mob1b^{Gt(CC0690)Wtsi} mutation (0 available); any Mob1b mutation (21 available)
Speer6-ps1^{Tg(Alb-cre)21Mgn} mutation (6 available); any Speer6-ps1 mutation (4 available)
Yap1^{tm1c(KOMP)Mbp} mutation (0 available); any Yap1 mutation (37 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

liver/biliary system

abnormal cholangiocyte morphology ( J:228499 )

• increased immature cholangiocyte-like and oval cells but far less than in Mob1a^tm1.1Asuz/Mob1a^tm1.1Asuz Mob1b^{Gt(CC0690)Wtsi}/Mob1b^{Gt(CC0690)Wtsi} Tg(Alb-cre)21Mgn mice

increased liver weight ( J:228499 )

• much less than in Mob1a^tm1.1Asuz/Mob1a^tm1.1Asuz Mob1b^{Gt(CC0690)Wtsi}/Mob1b^{Gt(CC0690)Wtsi} Tg(Alb-cre)21Mgn mice

liver fibrosis ( J:228499 )

• much less than in Mob1a^tm1.1Asuz/Mob1a^tm1.1Asuz Mob1b^{Gt(CC0690)Wtsi}/Mob1b^{Gt(CC0690)Wtsi} Tg(Alb-cre)21Mgn mice

endocrine/exocrine glands

abnormal cholangiocyte morphology ( J:228499 )

• increased immature cholangiocyte-like and oval cells but far less than in Mob1a^tm1.1Asuz/Mob1a^tm1.1Asuz Mob1b^{Gt(CC0690)Wtsi}/Mob1b^{Gt(CC0690)Wtsi} Tg(Alb-cre)21Mgn mice

growth/size/body

increased liver weight ( J:228499 )

• much less than in Mob1a^tm1.1Asuz/Mob1a^tm1.1Asuz Mob1b^{Gt(CC0690)Wtsi}/Mob1b^{Gt(CC0690)Wtsi} Tg(Alb-cre)21Mgn mice

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 05/07/2024 MGI 6.23