Phenotypes associated with this allele
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| Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gabrg2tm1Spet mutation
(3 available);
any
Gabrg2 mutation
(41 available)
n-TRtct5m1J mutation
(4 available);
any
n-TRtct5 mutation
(4 available)
Tg(n-TRtct5)574Slac mutation
(0 available)
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behavior/neurological
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• significant increase in SWD incidence
• normal SWD duration (i.e. same as on other genetic background)
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nervous system
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• significant increase in SWD incidence
• normal SWD duration (i.e. same as on other genetic background)
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| Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
n-TRtct5m1J mutation
(4 available);
any
n-TRtct5 mutation
(4 available)
Tg(n-TRtct5)574Slac mutation
(0 available)
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behavior/neurological
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N |
• normal seizure threshold in response to electrical stimulation or when treated with pentylenetetrazole (PTZ) [i.e. lower threshold than non-transgenic B6J mice, which carry the n-TRtct5m1J allele]
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| Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gtpbp2nmf205 mutation
(1 available);
any
Gtpbp2 mutation
(37 available)
Tg(n-TRtct5)574Slac mutation
(0 available)
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nervous system
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• although the cerebellum is not identical to Gtpbp2 wild-type controls, this transgene, which has brain-specific expression of wild-type n-Tr20, rescues most of the nmf205 mutant phenotype such that at 6 months of age the neuronal death is greatly attenuated in the brain and retina
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Analysis Tools