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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Setd1atm1.2Afst
targeted mutation 1.2, A Francis Stewart
MGI:5568941
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Setd1atm1.2Afst/Setd1atm1.2Afst involves: 129S1/Sv * 129X1/SvJ * BALB/c * C57BL/6 MGI:5568947
cn2
 		Setd1atm1.1Afst/Setd1atm1.2Afst
Tg(Gdf9-icre)5092Coo/0 		involves: 129S1/Sv * 129X1/SvJ * BALB/c * C57BL/6 MGI:5568949


Genotype
MGI:5568947
hm1
Allelic
Composition		 Setd1atm1.2Afst/Setd1atm1.2Afst
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * BALB/c * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Setd1atm1.2Afst mutation (0 available); any Setd1a mutation (60 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging

embryo
failure to gastrulate ( J:208420 )
• implant but fail to gastrulate




Genotype
MGI:5568949
cn2
Allelic
Composition		 Setd1atm1.1Afst/Setd1atm1.2Afst
Tg(Gdf9-icre)5092Coo/0
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * BALB/c * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Setd1atm1.1Afst mutation (0 available); any Setd1a mutation (60 available)
Setd1atm1.2Afst mutation (0 available); any Setd1a mutation (60 available)
Tg(Gdf9-icre)5092Coo mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
embryo
embryonic growth retardation ( J:208420 )
• at E6.5 and E7.5

growth/size/body
embryonic growth retardation ( J:208420 )
• at E6.5 and E7.5




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory