Phenotypes associated with this allele

• Allele Symbol: Hsd11b1^tm1.2Awhi
• Allele Name: targeted mutation 1.1, Anne White
• Allele ID: MGI:5566778
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Hsd11b1^tm1.2Awhi/Hsd11b1^tm1.2Awhi Tg(Nes-cre)1Kln/0	involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL	MGI:5566781

Genotype
MGI:5566781

cn1

• Allelic Composition: Hsd11b1^tm1.2Awhi/Hsd11b1^tm1.2Awhi; Tg(Nes-cre)1Kln/0
• Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

abnormal food intake ( J:207713 )

• in mice fed a high fat diet compared with Nes mice

• intake in mice fed a high fat diet is lower than in Hsd11b1^tm1.2Awhi homozygotes or C57BL/6J mice

growth/size/body

growth/size/body region phenotype ( J:207713 )

N • mice fed a high fat diet exhibit normal increase in weight and changes in body composition

homeostasis/metabolism

homeostasis/metabolism phenotype ( J:207713 )

N • mice exhibit normal circulating corticosterone levels

N • mice fed a high fat diet exhibit normal changed in glucose metabolism