All Phenotypes Slit3<b2b2362.1Clo> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Slit3^b2b2362.1Clo
Bench to Bassinet Program (B2B/CVDC) mutation 2362, subline 1, Cecilia Lo
MGI:5560156

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Slit3^b2b2362.1Clo/Slit3^b2b2362.1Clo	C57BL/6J-Slit3^b2b2362.1Clo	MGI:5560159

Allelic Composition	Slit3^b2b2362.1Clo/Slit3^b2b2362.1Clo
Genetic Background	C57BL/6J-Slit3^b2b2362.1Clo

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Slit3^b2b2362.1Clo mutation (1 available); any Slit3 mutation (80 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

Mutant 2362-004-1 (E16.5) exhibits ectopia cordis, ventricular non-compaction, and gastroschisis with a body wall closure defect

cardiovascular system

abnormal myocardial trabeculae morphology ( J:175213 )

• Excessive myocardial trabeculation or noncompaction

double outlet right ventricle with atrioventricular septal defect ( J:175213 )

double outlet right ventricle, Taussig bing type ( J:175213 )

ectopia cordis ( J:175213 )

ventricular septal defect ( J:175213 )

muscle

abnormal myocardial trabeculae morphology ( J:175213 )

• Excessive myocardial trabeculation or noncompaction

growth/size/body

herniated abdominal wall ( J:175213 )

renal glomerulus cyst ( J:175213 )

renal/urinary system

renal glomerulus cyst ( J:175213 )

renal hypoplasia ( J:175213 )

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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