Analysis Tools
nervous system
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• vomeronasal epithelium remains largely normal with normal layering
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• slight decrease of the number of basal vomeronasal sensory neurons at 10 weeks of age
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• while vomeronasal sensory neurons (VSN) that do not normally co-express H2-Mv genes have normal response to stimulation, VSNs that normally co-express H2-Mv genes have significantly diminished response to stimuli requiring much higher concentrations of specific peptide stimuli or exocrine gland secreted peptide 1, and have diminished response in electrovomerograms
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behavior/neurological
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• homozygous males and homozygous lactating females both show decreased aggression toward a castrated intruder male that has been swabbed with high molecular weight fraction of male urine
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• lactating females show a pronounced decrease towards intruder males
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• although homozygous males show no change in latency to mount, and homozygous females show no change in duration of investigation of the male anogenital region, homozygous females do display diminished lordosis behavior
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growth/size/body
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• slight decrease of the number of basal vomeronasal sensory neurons at 10 weeks of age
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respiratory system
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• slight decrease of the number of basal vomeronasal sensory neurons at 10 weeks of age
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craniofacial
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• slight decrease of the number of basal vomeronasal sensory neurons at 10 weeks of age
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