All Phenotypes Sirt3<tm1.1Auw> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Sirt3^tm1.1Auw
targeted mutation 1.1, Johan Auwerx
MGI:5556075

Summary

2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Sirt3^tm1.1Auw/Sirt3^tm1.1Auw Speer6-ps1^{Tg(Alb-cre)21Mgn}/Speer6-ps1⁺	involves: C57BL/6 * C57BL/6J * DBA	MGI:5556080
cn2	Sirt3^tm1.1Auw/Sirt3^tm1.1Auw Tg(ACTA1-cre)79Jme/0	involves: C57BL/6J * SJL	MGI:5556079

Allelic Composition	Sirt3^tm1.1Auw/Sirt3^tm1.1Auw Speer6-ps1^{Tg(Alb-cre)21Mgn}/Speer6-ps1⁺
Genetic Background	involves: C57BL/6 * C57BL/6J * DBA

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Sirt3^tm1.1Auw mutation (1 available); any Sirt3 mutation (30 available)
Speer6-ps1^{Tg(Alb-cre)21Mgn} mutation (6 available); any Speer6-ps1 mutation (4 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

homeostasis/metabolism

homeostasis/metabolism phenotype ( J:207274 )

N	• mice fed chow or a high-fat diet exhibit a normal metabolic phenotype

Allelic Composition	Sirt3^tm1.1Auw/Sirt3^tm1.1Auw Tg(ACTA1-cre)79Jme/0
Genetic Background	involves: C57BL/6J * SJL

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Sirt3^tm1.1Auw mutation (1 available); any Sirt3 mutation (30 available)
Tg(ACTA1-cre)79Jme mutation (2 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

homeostasis/metabolism

homeostasis/metabolism phenotype ( J:207274 )

N	• mice fed chow or a high-fat diet exhibit a normal metabolic phenotype

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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