All Phenotypes b2b2025.2Clo MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

b2b2025.2Clo
Bench to Bassinet Program (B2B/CVDC), mutation 2025, subline 2 Cecilia Lo
MGI:5554445

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	b2b2025.2Clo/b2b2025.2Clo	C57BL/6J-b2b2025.2Clo	MGI:5555836

Allelic Composition	b2b2025.2Clo/b2b2025.2Clo
Genetic Background	C57BL/6J-b2b2025.2Clo

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
b2b2025.2Clo mutation (1 available); any b2b2025.2Clo mutation (1 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

Mutant 2025-007-1 (E16.5) presents with malaligned great arteries, right aortic arch (RAA), and hypoplastic pulmonary artery

cardiovascular system

pulmonary artery hypoplasia ( J:175213 )

abnormal aortic arch morphology ( J:175213 )

right aortic arch ( J:175213 )

vascular ring ( J:175213 )

abnormal myocardium compact layer morphology ( J:175213 )

• excessive myocardial trabeculation or noncompaction

double outlet right ventricle ( J:175213 )

double outlet right ventricle with atrioventricular septal defect ( J:175213 )

atrioventricular septal defect ( J:175213 )

limbs/digits/tail

abnormal autopod morphology ( J:175213 )

syndactyly ( J:175213 )

vision/eye

microphthalmia ( J:175213 )

muscle

abnormal myocardium compact layer morphology ( J:175213 )

• excessive myocardial trabeculation or noncompaction

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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