Phenotypes associated with this allele
|
Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rhbdf1tm1.1Mfm mutation
(0 available);
any
Rhbdf1 mutation
(43 available)
|
|
|
mortality/aging
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• mice die between P9 and P20
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behavior/neurological
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• with hind legs being particularly affected
|
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• uncoordinated with hind legs being particularly affected
|
|
Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rhbdf1tm1.1Mfm mutation
(0 available);
any
Rhbdf1 mutation
(43 available)
|
|
|
mortality/aging
|
• mice survive 25 to 40 days
|
behavior/neurological
|
• obsessive eating around time of weaning
|
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• transient around 14 to 18 days
|
growth/size/body
nervous system
cardiovascular system
|
Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rhbdf1tm1.1Mfm mutation
(0 available);
any
Rhbdf1 mutation
(43 available)
|
|
|
mortality/aging
endocrine/exocrine glands
hematopoietic system
N |
• erythroid, myeloid and megakaryocyte maturation appear normal
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growth/size/body
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• small and malnourished 6 to 14 days after birth
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• mice fail to gain weight after birth
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adipose tissue
cardiovascular system
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• evidence of myocardial infarction with thrombi in and around the ventricular septum close to the site of infarction
|
homeostasis/metabolism
digestive/alimentary system
immune system
|
Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rhbdf1tm1.1Mfm mutation
(0 available);
any
Rhbdf1 mutation
(43 available)
Rhbdf2tm1.1Mfm mutation
(1 available);
any
Rhbdf2 mutation
(84 available)
|
|
|
mortality/aging
reproductive system
|
Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rhbdf1tm1.1Mfm mutation
(0 available);
any
Rhbdf1 mutation
(43 available)
Rhbdf2tm1.1Mfm mutation
(1 available);
any
Rhbdf2 mutation
(84 available)
|
|
|
mortality/aging
|
• no mice beyond E9.5 to E10.5
|
|
Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rhbdf1tm1.1Mfm mutation
(0 available);
any
Rhbdf1 mutation
(43 available)
Rhbdf2tm1.1Mfm mutation
(1 available);
any
Rhbdf2 mutation
(84 available)
|
|
|
mortality/aging
|
• no mice beyond E9.5 to E10.5
|
|
Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rhbdf1tm1.1Mfm mutation
(0 available);
any
Rhbdf1 mutation
(43 available)
Rhbdf2tm1.1Mfm mutation
(1 available);
any
Rhbdf2 mutation
(84 available)
|
|
|
mortality/aging
reproductive system