Phenotypes associated with this allele

• Allele Symbol: Psph^{tm1.1(KOMP)Vlcg}
• Allele Name: targeted mutation 1.1, Velocigene
• Allele ID: MGI:5548963
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Psph^tm1.1(KOMP)Vlcg/Psph^tm1.1(KOMP)Vlcg	C57BL/6N-Psph^tm1.1(KOMP)Vlcg/Ucd	MGI:5757579
ht2	Psph^tm1.1(KOMP)Vlcg/Psph^+	C57BL/6N-Psph^tm1.1(KOMP)Vlcg/Ucd	MGI:5757578

Genotype
MGI:5757579

hm1

• Allelic Composition: Psph^{tm1.1(KOMP)Vlcg}/Psph^{tm1.1(KOMP)Vlcg}
• Genetic Background: C57BL/6N-Psph^{tm1.1(KOMP)Vlcg}/Ucd
• Cell Lines: 11763C-D1

Data Sources

IMPC Data for Psph

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

abnormal heart morphology ( J:211773 )

IMPC - TCP

craniofacial

abnormal craniofacial morphology ( J:211773 )

IMPC - TCP

embryo

abnormal embryo size ( J:211773 )

IMPC - TCP

pale placenta ( J:211773 )

IMPC - TCP

pale yolk sac ( J:211773 )

IMPC - TCP

growth/size/body

abnormal embryo size ( J:211773 )

IMPC - TCP

homeostasis/metabolism

edema ( J:211773 )

IMPC - TCP

integument

pallor ( J:211773 )

IMPC - TCP

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - TCP

vision/eye

abnormal eye morphology ( J:211773 )

IMPC - TCP

microphthalmia ( J:211773 )

IMPC - TCP

anophthalmia ( J:211773 )

IMPC - TCP

Genotype
MGI:5757578

ht2

• Allelic Composition: Psph^{tm1.1(KOMP)Vlcg}/Psph⁺
• Genetic Background: C57BL/6N-Psph^{tm1.1(KOMP)Vlcg}/Ucd
• Cell Lines: 11763C-D1

Data Sources

IMPC Data for Psph

cardiovascular system

cardiovascular system phenotype ( J:211773 )

♀

IMPC - TCP

increased heart rate variability ( J:211773 )

♀

IMPC - TCP

endocrine/exocrine glands

small adrenal glands ( J:211773 )

♂

IMPC - TCP

hematopoietic system

thrombocytopenia ( J:211773 )

♂

IMPC - TCP

homeostasis/metabolism

decreased circulating triglyceride level ( J:211773 )

♂

IMPC - TCP