Phenotypes associated with this allele

• Allele Symbol: Acat2^{tm1b(KOMP)Wtsi}
• Allele Name: targeted mutation 1b, Wellcome Trust Sanger Institute
• Allele ID: MGI:5548912
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Acat2^tm1b(KOMP)Wtsi/Acat2^tm1b(KOMP)Wtsi	C57BL/6N-Acat2^tm1b(KOMP)Wtsi/Bay	MGI:5756641
ht2	Acat2^tm1b(KOMP)Wtsi/Acat2^+	C57BL/6N-Acat2^tm1b(KOMP)Wtsi/Bay	MGI:5767553

Genotype
MGI:5756641

hm1

• Allelic Composition: Acat2^{tm1b(KOMP)Wtsi}/Acat2^{tm1b(KOMP)Wtsi}
• Genetic Background: C57BL/6N-Acat2^{tm1b(KOMP)Wtsi}/Bay
• Cell Lines: EPD0797_6_H04

Data Sources

IMPC Data for Acat2

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

unresponsive to tactile stimuli ( J:211773 )

IMPC - BCM

embryo

abnormal embryo size ( J:211773 )

IMPC - BCM

growth/size/body

abnormal embryo size ( J:211773 )

IMPC - BCM

abnormal body wall morphology ( J:211773 )

IMPC - BCM

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - BCM

Genotype
MGI:5767553

ht2

• Allelic Composition: Acat2^{tm1b(KOMP)Wtsi}/Acat2⁺
• Genetic Background: C57BL/6N-Acat2^{tm1b(KOMP)Wtsi}/Bay
• Cell Lines: EPD0797_6_H04

Data Sources

IMPC Data for Acat2

behavior/neurological

unresponsive to tactile stimuli ( J:211773 )

IMPC - BCM

growth/size/body

increased body length ( J:211773 )

IMPC - BCM

homeostasis/metabolism

increased circulating chloride level ( J:211773 )

♀

IMPC - BCM