Phenotypes associated with this allele

• Allele Symbol: Klhl29^{tm1b(EUCOMM)Hmgu}
• Allele Name: targeted mutation 1b, Helmholtz Zentrum Muenchen GmbH
• Allele ID: MGI:5548861
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Klhl29^tm1b(EUCOMM)Hmgu/Klhl29^tm1b(EUCOMM)Hmgu	C57BL/6N-Klhl29^tm1b(EUCOMM)Hmgu/Ics	MGI:5757292
ht2	Klhl29^tm1b(EUCOMM)Hmgu/Klhl29^+	C57BL/6N-Klhl29^tm1b(EUCOMM)Hmgu/Ics	MGI:5757291

Genotype
MGI:5757292

hm1

• Allelic Composition: Klhl29^{tm1b(EUCOMM)Hmgu}/Klhl29^{tm1b(EUCOMM)Hmgu}
• Genetic Background: C57BL/6N-Klhl29^{tm1b(EUCOMM)Hmgu}/Ics
• Cell Lines: HEPD0530_1_C09

Data Sources

IMPC Data for Klhl29

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

increased cardiac muscle contractility ( J:211773 )

♂

IMPC - ICS

increased heart rate ( J:211773 )

♂

IMPC - ICS

homeostasis/metabolism

decreased respiratory quotient ( J:211773 )

♂

IMPC - ICS

mortality/aging

preweaning lethality, incomplete penetrance ( J:211773 )

IMPC - ICS

muscle

increased cardiac muscle contractility ( J:211773 )

♂

IMPC - ICS

Genotype
MGI:5757291

ht2

• Allelic Composition: Klhl29^{tm1b(EUCOMM)Hmgu}/Klhl29⁺
• Genetic Background: C57BL/6N-Klhl29^{tm1b(EUCOMM)Hmgu}/Ics
• Cell Lines: HEPD0530_1_C09

Data Sources

IMPC Data for Klhl29

cardiovascular system

prolonged QT interval ( J:211773 )

♀

IMPC - ICS

prolonged ST segment ( J:211773 )

♀

IMPC - ICS

hematopoietic system

increased large unstained cell number ( J:211773 )

♂

IMPC - ICS

immune system

increased large unstained cell number ( J:211773 )

♂

IMPC - ICS