All Phenotypes Med28<tm1.1(KOMP)Vlcg> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Med28^{tm1.1(KOMP)Vlcg}
targeted mutation 1.1, Velocigene
MGI:5548528

Summary

4 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Med28^{tm1.1(KOMP)Vlcg}/Med28^{tm1.1(KOMP)Vlcg}	C57BL/6N-Med28^{tm1.1(KOMP)Vlcg}/MbpMmucd	MGI:6325153
hm2	Med28^{tm1.1(KOMP)Vlcg}/Med28^{tm1.1(KOMP)Vlcg}	C57BL/6N-Med28^{tm1.1(KOMP)Vlcg}/Ucd	MGI:5767722
ht3	Med28^{tm1.1(KOMP)Vlcg}/Med28⁺	C57BL/6N-Med28^{tm1.1(KOMP)Vlcg}/MbpMmucd	MGI:6325152
ht4	Med28^{tm1.1(KOMP)Vlcg}/Med28⁺	C57BL/6N-Med28^{tm1.1(KOMP)Vlcg}/Ucd	MGI:5757354

Allelic Composition	Med28^{tm1.1(KOMP)Vlcg}/Med28^{tm1.1(KOMP)Vlcg}
Genetic Background	C57BL/6N-Med28^{tm1.1(KOMP)Vlcg}/MbpMmucd
Cell Lines	11940A-A8

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Med28^{tm1.1(KOMP)Vlcg} mutation (1 available); any Med28 mutation (16 available)

Data Sources

IMPC Data for Med28

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

embryonic lethality prior to tooth bud stage ( J:211773 )

IMPC - TCP

embryonic lethality prior to organogenesis ( J:211773 )

IMPC - TCP

Allelic Composition	Med28^{tm1.1(KOMP)Vlcg}/Med28^{tm1.1(KOMP)Vlcg}
Genetic Background	C57BL/6N-Med28^{tm1.1(KOMP)Vlcg}/Ucd
Cell Lines	11940A-A8

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Med28^{tm1.1(KOMP)Vlcg} mutation (1 available); any Med28 mutation (16 available)

Data Sources

IMPC Data for Med28

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - UCD

Allelic Composition	Med28^{tm1.1(KOMP)Vlcg}/Med28⁺
Genetic Background	C57BL/6N-Med28^{tm1.1(KOMP)Vlcg}/MbpMmucd
Cell Lines	11940A-A8

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Med28^{tm1.1(KOMP)Vlcg} mutation (1 available); any Med28 mutation (16 available)

Data Sources

IMPC Data for Med28

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

embryo

abnormal embryo size ( J:211773 )

IMPC - TCP

growth/size/body

abnormal embryo size ( J:211773 )

IMPC - TCP

Allelic Composition	Med28^{tm1.1(KOMP)Vlcg}/Med28⁺
Genetic Background	C57BL/6N-Med28^{tm1.1(KOMP)Vlcg}/Ucd
Cell Lines	11940A-A8

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Med28^{tm1.1(KOMP)Vlcg} mutation (1 available); any Med28 mutation (16 available)

Data Sources

IMPC Data for Med28

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

growth/size/body

increased body length ( J:211773 )

IMPC - UCD

hearing/vestibular/ear

abnormal auditory brainstem response ( J:211773 )

IMPC - UCD

hematopoietic system

abnormal spleen morphology ( J:211773 )

IMPC - UCD

small spleen ( J:211773 )

IMPC - UCD

homeostasis/metabolism

decreased circulating serum albumin level ( J:211773 )

IMPC - UCD

increased respiratory quotient ( J:211773 )

IMPC - UCD

immune system

abnormal spleen morphology ( J:211773 )

IMPC - UCD

small spleen ( J:211773 )

IMPC - UCD

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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