Phenotypes associated with this allele

• Allele Symbol: Atn1^{tm1b(EUCOMM)Wtsi}
• Allele Name: targeted mutation 1b, Wellcome Trust Sanger Institute
• Allele ID: MGI:5548352
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Atn1^tm1b(EUCOMM)Wtsi/Atn1^tm1b(EUCOMM)Wtsi	C57BL/6N-Atn1^tm1b(EUCOMM)Wtsi/Cnrm	MGI:5756742

Genotype
MGI:5756742

hm1

• Allelic Composition: Atn1^{tm1b(EUCOMM)Wtsi}/Atn1^{tm1b(EUCOMM)Wtsi}
• Genetic Background: C57BL/6N-Atn1^{tm1b(EUCOMM)Wtsi}/Cnrm
• Cell Lines: EPD0289_1_F08

Data Sources

IMPC Data for Atn1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

decreased exploration in new environment ( J:211773 )

♀

IMPC - HAR

limb grasping ( J:211773 )

IMPC - HAR

abnormal gait ( J:211773 )

♀

IMPC - HAR

cardiovascular system

cardiovascular system phenotype ( J:211773 )

♀

IMPC - HAR

abnormal heart morphology ( J:211773 )

♂

IMPC - HAR

abnormal sinus arrhythmia ( J:211773 )

IMPC - HAR

increased heart rate variability ( J:211773 )

IMPC - HAR

hematopoietic system

decreased erythrocyte cell number ( J:211773 )

♀

IMPC - HAR

increased mean corpuscular hemoglobin ( J:211773 )

IMPC - HAR

increased neutrophil cell number ( J:211773 )

♂

IMPC - HAR

decreased lymphocyte cell number ( J:211773 )

♂

IMPC - HAR

decreased monocyte cell number ( J:211773 )

IMPC - HAR

homeostasis/metabolism

increased circulating triglyceride level ( J:211773 )

♀

IMPC - HAR

decreased circulating serum albumin level ( J:211773 )

♂

IMPC - HAR

immune system

increased neutrophil cell number ( J:211773 )

♂

IMPC - HAR

decreased lymphocyte cell number ( J:211773 )

♂

IMPC - HAR

decreased monocyte cell number ( J:211773 )

IMPC - HAR

integument

abnormal skin morphology ( J:211773 )

IMPC - HAR

vision/eye

cataract ( J:211773 )

IMPC - HAR

persistence of hyaloid vascular system ( J:211773 )

♂

IMPC - HAR