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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Droshatm1.1Vlcg
targeted mutation 1.1, Velocigene
MGI:5544789
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Droshatm1.1Vlcg/Droshatm1.1Vlcg involves: 129S6/SvEvTac * C57BL/6NTac MGI:5546233
cn2
 		Droshatm1.1Vlcg/Droshatm3Vlcg
Gt(ROSA)26Sortm3.1(cre/ERT2)Vlcg/Gt(ROSA)26Sor+ 		involves: 129S6/SvEvTac * C57BL/6NTac MGI:5546236


Genotype
MGI:5546233
hm1
Allelic
Composition		 Droshatm1.1Vlcg/Droshatm1.1Vlcg
Genetic
Background		 involves: 129S6/SvEvTac * C57BL/6NTac
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Droshatm1.1Vlcg mutation (0 available); any Drosha mutation (98 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype




Genotype
MGI:5546236
cn2
Allelic
Composition		 Droshatm1.1Vlcg/Droshatm3Vlcg
Gt(ROSA)26Sortm3.1(cre/ERT2)Vlcg/Gt(ROSA)26Sor+
Genetic
Background		 involves: 129S6/SvEvTac * C57BL/6NTac
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Droshatm1.1Vlcg mutation (0 available); any Drosha mutation (98 available)
Droshatm3Vlcg mutation (0 available); any Drosha mutation (98 available)
Gt(ROSA)26Sortm3.1(cre/ERT2)Vlcg mutation (0 available); any Gt(ROSA)26Sor mutation (1046 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
mortality/aging ( J:200671 )
N
• tamoxifen-treated mice are born and survive

growth/size/body
decreased body size ( J:200671 )
• tamoxifen-treated mice are runted




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory