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Allele Symbol Allele Name Allele ID |
Mcfd2tm1Dgi targeted mutation 1, David Ginsburg MGI:5544759 |
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| Summary |
2 genotypes
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• increased factor V and aspartate transaminase levels in the liver with retention in the ER
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• decreased factor V and VIII serum levels
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• small decrease in male, but not female, mice with accumulation in the ER
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• increased factor V and aspartate transaminase levels in the liver with retention in the ER
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• decreased factor V and VIII serum levels but not as much as in Mcfd2tm1Dgi homozygotes
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• small decrease in male, but not female, mice with accumulation in the ER
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/14/2024 MGI 6.23 |
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