Analysis Tools
nervous system
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• mice exposed to hyperthermia fail to exhibit progression of seizures beyond score 3 with complete absence of electrographic seizures compared with wild-type mice
• mice exhibit atypical experimental febrile seizures compared with wild-type mice
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• under current clamp conditions, the slope of the depolarizing shift is lower than in wild-type neurons
• GABA application injected at the stratum radiatum and stratum lacunosum-moleculare border evokes hardly any spiking even with the longest puff compared with wild-type neurons
• dendritic GABA-evoked depolarization is smaller in neurons from P12 to P16 neurons compared with wild-type neurons
• however, measurement under voltage clamp conditions are normal
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behavior/neurological
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• mice exposed to hyperthermia fail to exhibit progression of seizures beyond score 3 with complete absence of electrographic seizures compared with wild-type mice
• mice exhibit atypical experimental febrile seizures compared with wild-type mice
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