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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Mirc15tm1.2Flv
targeted mutation 1.2, Richard A Flavell
MGI:5528992
Summary 3 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Mirc15tm1.2Flv/Mirc15tm1.2Flv involves: C57BL/6 * C57BL/6N * FVB/N * SJL MGI:5529030
cx2
 		Mirc14tm1.2Flv/Mirc14tm1.2Flv
Mirc15tm1.2Flv/Mirc15tm1.2Flv 		involves: C57BL/6 * C57BL/6N * FVB/N * SJL MGI:5529026
cx3
 		Mirc14tm1.2Flv/Mirc14tm1.2Flv
Mirc15tm1.2Flv/Mirc15tm1.2Flv
Mirc16tm1.2Flv/Mirc16tm1.2Flv 		involves: C57BL/6 * C57BL/6N * FVB/N * SJL MGI:5529028


Genotype
MGI:5529030
hm1
Allelic
Composition		 Mirc15tm1.2Flv/Mirc15tm1.2Flv
Genetic
Background		 involves: C57BL/6 * C57BL/6N * FVB/N * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mirc15tm1.2Flv mutation (0 available); any Mirc15 mutation (2 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype
no abnormal phenotype detected ( J:203157 )
• mice are obtained in normal Mendelian ratios and do not exhibit abnormalities in terms of growth, development, survival or NKT cell development




Genotype
MGI:5529026
cx2
Allelic
Composition		 Mirc14tm1.2Flv/Mirc14tm1.2Flv
Mirc15tm1.2Flv/Mirc15tm1.2Flv
Genetic
Background		 involves: C57BL/6 * C57BL/6N * FVB/N * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mirc14tm1.2Flv mutation (0 available); any Mirc14 mutation (1 available)
Mirc15tm1.2Flv mutation (0 available); any Mirc15 mutation (2 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging

immune system
decreased B cell number ( J:203157 )
• in the bone marrow

growth/size/body
decreased body weight ( J:203157 )

hematopoietic system
decreased B cell number ( J:203157 )
• in the bone marrow




Genotype
MGI:5529028
cx3
Allelic
Composition		 Mirc14tm1.2Flv/Mirc14tm1.2Flv
Mirc15tm1.2Flv/Mirc15tm1.2Flv
Mirc16tm1.2Flv/Mirc16tm1.2Flv
Genetic
Background		 involves: C57BL/6 * C57BL/6N * FVB/N * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mirc14tm1.2Flv mutation (0 available); any Mirc14 mutation (1 available)
Mirc15tm1.2Flv mutation (0 available); any Mirc15 mutation (2 available)
Mirc16tm1.2Flv mutation (0 available); any Mirc16 mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
lethality, complete penetrance ( J:203157 )
• mice have yet to be obtained indicating incompatibility with life




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory